When we eat too many carbs our insulin will increase production of triglycerides when it can't get all the sugars into our cells. This is the end result of insulin resistance which many of us have, and all adult diabetics and pre-diabetics have. The triglycerides are stored in our fat cells which then swell and we get fatter.
Even though we may try to diet by eating less, take supplements and follow other weight loss practices, often we fail to lose weight. The problem likely is in our fat cells and the signaling system they have with our brain. Fat cells (adipocytes) secrete three hormone signals that the brain can interpret to determine how much fat we have stored. When working properly these three - leptin, adiponectin, and glycerol-3-phosphate dehydrogenase - will rise with increasing fat and the brain will respond appropriately to prevent us from making more fat.
Leptin is supposed to signal the brain when enough food has been consumed and shuts down appetite. It then signals the fat cells holding all those triglycerides stores to burn off the fat. But the leptin receptors on cells become resistant to leptin just as the insulin receptors become resistant to insulin. This happens when we eat too many pro-inflammatory foods on a daily basis. Dr. Galland published "The Fat Resistance Diet" a few years ago and it contains the foods that turn off this inflammatory response and increase leptin sensitivity. I have recommended this diet to many people and seen weight loss occur when they follow it. It is easy to follow, based on very healthy recipes that are easy to prepare and the tastes are awesome! I was able to purchase every food and spice in this diet right here in Liberal, KS. I highly suggest you purchase this book and follow it when you are on a weight loss program. It can also help any inflammaory disease such as arthritis, asthma, allergy and polycystic ovary syndrome. Sugar craving is markedly reduced on this diet. The new supplement, Irvingia gabonensis, also improves leptin receptor sensitivity on fat cells in addition to this diet.
Adiponectin is increased when you have more fat cells and actually helps protect your arteries from plaque damage and the increased adiponectin also improver insulin sensitivity. Irvinigia gabonensis increases adiponectin levels in the blood.
Glycerol-3-phopsphate dehydrogenase (G3PD) increases the conversion of blood sugar into stored triglycerides and must be decreased in amount and activity to slow your building of fat. This enzyme is inhibited by Irvingia.
These three hormones must be addressed in any weight reduction program you begin. I now have in the office a new supplement containing Irvingia gabonensis. In a double-blind study using this Irvingia gabonensis, over 6 months use with no dietary restriction, resulted in an average weight loss of 24 pounds in the participants.
drBob
